Influence of Actuator Nozzle Angle on the Flow Characteristics in Pressurized-Metered Dose Inhaler Using CFD

Muhammad Faqhrurrazi  Abd Rahman; Nor Zelawati  Asmuin; Ishkrizat  Taib; Mohamad Nur Hidayat  Mat; Riyadhthusollehan  Khairulfuaad

Authors

Muhammad Faqhrurrazi Abd Rahman Department of Thermofluids Engineering, Faculty of Mechanical and Manufacturing Engineering, Universiti Tun Hussein Onn, 86400 Parit Raja, Johor, Malaysia
Nor Zelawati Asmuin Department of Thermofluids Engineering, Faculty of Mechanical and Manufacturing Engineering, Universiti Tun Hussein Onn, 86400 Parit Raja, Johor, Malaysia
Ishkrizat Taib Department of Thermofluids Engineering, Faculty of Mechanical and Manufacturing Engineering, Universiti Tun Hussein Onn, 86400 Parit Raja, Johor, Malaysia
Mohamad Nur Hidayat Mat Department of Thermofluids Engineering, Faculty of Mechanical and Manufacturing Engineering, Universiti Tun Hussein Onn, 86400 Parit Raja, Johor, Malaysia
Riyadhthusollehan Khairulfuaad Department of Thermofluids Engineering, Faculty of Mechanical and Manufacturing Engineering, Universiti Tun Hussein Onn, 86400 Parit Raja, Johor, Malaysia

Keywords:

alveolar, angle, pressurized metered dose inhalers, simulation

Abstract

Pressurized metered dose inhalers (pMDIs) are often used for the treatment of asthma and chronic obstructive pulmonary disease. This device is easy to carry, highly effective and extremely safe, allowing reliable, consistent dosage delivery, metered dose inhalers are the inhalation devices that doctors and patients can readily select from around the world. This pMDI inhaler system has a problem which is the particle does not penetrate into the alveolar. ANSYS Fluent Version 19.2 was used to find the best angle of the actuator nozzle by parametric analysis. Standard K-epsilon was used as the turbulence model with enhanced wall treatment function. Discrete phase model (DPM) was applied to represent the particle flow. The result shows the best actuator nozzle angle is 120-degree which affects the maximum magnitude of particle velocity.